The Best IGF-1 Supplements, Pills and Sprays

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Top 3 Best IGF-1 Supplements of 2024 – Quick View

PGH-1000 product image

#1: PGH-1000

Rating: 5/5

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GenF20 Plus product photo

#2: GenF20 Plus

Rating: 4.9/5

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#3: Sytropin

Rating: 4.8/5

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Why You Cannot Avoid Your Diminishing IGF-1 Levels!

older male bodybuilder showing muscles

By the time you reach 60, your overall IGF-1 levels will generally be only a third of what they were when you were 20.

The result of having such diminished IGF-1 production? You’ll almost certainly have significantly less stamina, a greater percentage of body fat, take longer to heal, and have a weakened immune system.

Although both HGH and IGF-1 production diminish as you age, it is possible to increase your IGF-1 levels  naturally by making a few lifestyle changes.

Although both HGH and IGF-1 production diminish as you age, it is possible to increase your IGF-1 levels  naturally by making a few lifestyle changes.


IGF-1 can be restored naturally in four different ways:

  • Regular Exercise Working out on a regular basis will  gradually lead to a natural increase of IGF-1 production.
  • Getting Enough Sleep Growth hormone and IGF-1 levels are directly linked to deep sleep. If you aren’t getting enough, your levels will suffer.
  • IGF-1-Boosting Foods – There are certain foods containing high levels of nutrients, such as zinc, magnesium, and taurine that can encourage the natural production of IGF-1.
  • IGF-1 Supplements These supplements are formulated to offer all the advantages of having increased IGF-1 levels without  negative side effects, since they’re 100% natural. You experience many of the same benefits that HGH injections give without any of the negative effects associated with these treatments.

What Are IGF-1 Supplements?

IGF-1 Supplements are specially formulated to naturally increase the body’s production of IGF-1 (insulin-like growth factor). IGF-1 is so-named because it is very similar to insulin in its structure.

IGF-1 belongs to a group of peptides called somatomedins, and is an endocrine hormone that’s chiefly produced by the liver. While HGH (human growth hormone) is well known for it’s influence on cell growth, healing, and overall body development, it is IGF-1 that actually produces most of these effects.

Simply put, HGH stimulates the liver to start IGF-1 production – and that’s when all the magic happens.

The body’s production of IGF-1 is typically at its peak in adolescence and during puberty, then quickly declines during adulthood. However, adults who take IGF-1 supplements to boost their IGF-1 levels can reap significant health benefits as a result.

Why Use IGF-1 Supplements?

More and more people are turning to all-natural IGF-1 supplementation to enjoy the benefits of increased IGF-1 for greater muscle mass and fat loss, as well as shaving years off of their appearance.  IGF-1 supplements can trigger the body into naturally increasing its own production of IGF-1, which can result in enhanced cell growth and development, and many other anti-aging effects, such as:

  • Increased lean muscle mass
  • Elevated metabolic rate and fat loss
  • Gains in both strength and endurance
  • Enhanced immune function
  • Faster healing and recovery rates
  • Greater sex drive
  • Improved brain function
  • Stronger muscles, ligaments and tendons
  • Healthier, smoother, more resilient skin

These supplements are typically made from all-natural ingredients, are cost-effective, and safe to use. This makes them an ideal alternative to expensive prescription drugs or injections that can come with a number of side effects.

Best HGH Supplements
Using the right IGF-1 supplements can result in a dramatic reversal of the aging process.

How We Selected the Best IGF-1 Supplements

Our aim at Nutritional Supplements Directory is to guide you through the often complicated process of choosing which supplements actually work.

Our goal is to assist you with selecting an IGF-1 supplement that is both safe and effective in order to naturally elevate your IGF-1 production – so you’ll never have to experience the unpleasant side effects associated with synthetic IGF-1 injections.

After reviewing and examining a number of products, we created this list of the top IGF-1 Supplements which were rated based on the following criteria:

  • How effective is the supplement?
  • How quickly does the product work?
  • Is the formula made with only high-quality ingredients?
  • Is the supplement safe?
  • How easy is the product to use?
  • Is the product reasonably priced?
  • Does the manufacturer offer a money-back guarantee?
  • Are there any discounts available?
  • Does the supplement have a significant amount of repeat customers?
  • Is the customer service helpful and responsive?

These are the types of questions you should be asking yourself when deciding which IGF-1 supplement to buy – or any other nutritional supplement for that matter.

Our List of the Top 3 IGF-1 Supplements

#1. Pituitary Growth Hormone

Pituitary Growth Hormone supplement bottle on white background


Pituitary Growth Hormone (also called pGH) is our top pick for the best IGF-1 supplement, and it’s hands-down the best we have ever reviewed and tested. Designed to stimulate the growth of  lean muscle mass, increase strength and stamina, boost fat reduction, and enhance brain function, Pituitary Growth Hormone is an effective solution to hormone optimization.

Formulated to naturally trigger anabolic activity and metabolic function, this product is a perfect athletic performance supplement for promoting lean muscle growth and fitness enhancement. pGH stimulates the metabolism in a way that promotes lean body mass with minimal gains in body fat, all while improving a number of other health benefits, including improved sleep, quicker healing and recovery, and mood enhancement.

Users of Pituitary Growth Hormone typically experience the following benefits:

  • Enhances physical conditioning.
  • Increases lean muscle mass.
  • Promotes fat loss.
  • Improves recovery and joint protection.
  • Boosts strength and stamina.

Pituitary Growth Hormone is one of the most powerful and effective products we’ve tested, and most other supplements don’t even come close. If you’re in the market for dramatic improvements in physical performance and overall fitness, Pituitary Growth Hormone is a must-try.

Notice: Although this product is made with naturally-sourced ingredients, it is possible that it could cause you to test positive for performance enhancing drugs. If you are subject to testing by the IOC or other sports governing body, it is recommended that you first check with your organization’s drug-testing policies regarding the use of over the counter supplements before trying this product.

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#2. GenF20 Plus

GenF20 Plus tablets box and spray bottle on white background


GenF20 Plus is the best option for those who are looking for an IGF-1 supplement primarily to fight against the effects of aging. This supplement has shown the greatest rate of success for its anti-aging benefits and showed remarkable results for every single individual who used it that we surveyed.

Our research indicates that this high rate of success is directly tied to its use of a fully comprehensive formula, which provides a much larger dose of quality ingredients compared to many of the other products we tested. It’s formulated with a research-backed blend of herbal extracts, amino acids, and other growth factor ingredients that lead to muscle growth, stronger bones, increased energy, improved mood, a younger appearance, and many other benefits.

In fact, an 11-week double-blind clinical study demonstrated that GenF20 Plus increased IGF-1 levels by an average of 28%.

One of the reasons for GenF20’s effectiveness is that it incorporates its ingredients in both a pill and spray. Completely safe to use and free from side-effects, its double-pronged delivery system leads to an ultra-efficient absorption that inevitably results in physiological age-reversing changes in the body.

Some of the most common benefits that users experience include:

  • Diminishes fine lines and wrinkles.
  • Increases body strength and stamina.
  • Encourages weight loss and decreased body fat.
  • Promotes lean muscle growth.
  • Speeds up the metabolism.

When you combine the benefits you get with the overall safety, discount package pricing, and a generous 67-day money-back guarantee, GenF20 Plus is a no-brainer when it comes to physical fitness, fat loss, and a having a more youthful-looking appearance.

For a closer look at this product, be sure to check out my complete GenF20 Plus review.

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#3. Sytropin

Sytropin bottles on white background


Sytropin is an oral spray “secretogogue” supplement containing a number of  ingredients that are formulated to boost the production of IGF-1 within the body. A secretogogue is a substance that stimulates the release of certain hormones, such as HGH or IGF-1, potentially increasing lean muscle mass and energy levels while decreasing body fat, along with many other benefits.

Sytropin’s formula consists of a number of specific growth factors and amino acids that have been linked to an increase in IGF-1 levels. When used as directed, this product can lead to benefits very similar to those experienced when receiving doctor-prescribed IGF-1 injections – but in a far more convenient and easy-to-use method.

To use Sytropin you just need to apply two sprays under your tongue every morning, then keeping it there for two minutes to absorb into the bloodstream before swallowing. Within three short months, you should see first-hand the full effects, without experiencing any of the negative side effects associated with prescription treatments.

Whether you’re after a muscular physique, enhanced athletic performance, or just restoring your IGF-1 levels so you can regain your youthful vigor, I believe many of you will be amazed at the type of results you’ll experience when using Sytropin along with a healthy diet and fitness plan.

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IGF-1 Supplement FAQ

Here are some answers to the most commonly asked questions regarding the use of IGF-1 supplementation.

Are These IGF-1 Supplements Safe?

The majority of IGF-1 supplements currently being sold are made up completely natural ingredients and do not contain illegal steroids or harmful chemicals. However, simply because a product is marketed as “all natural” doesn’t necessarily mean that it’s “risk-free”.

But in the majority of cases, when used according to the manufacturer’s recommendations, most IGF-1 supplements are safe to take, do not cause side effects, and pose no serious health risks.

Are These HGH Supplements Guaranteed to Work?

Yes. As part of our IGF-1 supplement review process, we make sure that all products being reviewed are backed with a valid return and refund guarantee by the manufacturer. All of the supplements we review have been guaranteed to work as advertised or you can simply send back the packaging and/or unused portions for a full refund.

What Kind of Ingredients Are Used in IGF-1 Supplements?

Many of the ingredients used in IGF-1 supplements are often those used in HGH products. In fact, most HGH supplements work by increasing IGF-1 levels.

Some of the ingredients you’ll find in IGF-1 supplements include things like:

  • Herbal extracts
  • Amino acids
  • Vitamins and/or minerals
  • GABA
  • Colostrum
  • Pituitary extract

Additionally, deer antler velvet is another ingredient commonly used as an ingredient for raising IGF-1 levels is. At one time banned by the World Anti-Doping Agency, deer antler velvet possesses several powerful growth factors, including IGF-1.

As a result, these types of supplements are a commonly used by bodybuilders, athletes, and those seeking anti-aging benefits.

See Also: Top 5 Best HGH Supplements – The Ones That REALLY Work!

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